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Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes | Journal of Medicinal Chemistry
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes | Journal of Medicinal Chemistry

Frontiers | The Therapeutic Potential of Targeting NIK in B Cell Malignancies
Frontiers | The Therapeutic Potential of Targeting NIK in B Cell Malignancies

Cancers | Free Full-Text | Targeting NF-κB Signaling for Multiple Myeloma | HTML
Cancers | Free Full-Text | Targeting NF-κB Signaling for Multiple Myeloma | HTML

Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo | Journal of Medicinal Chemistry
Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo | Journal of Medicinal Chemistry

NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways | Cell Death & Disease
NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways | Cell Death & Disease

Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A

B022 | NIK Inhibitor | MedChemExpress
B022 | NIK Inhibitor | MedChemExpress

Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A

SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation | Science Signaling
SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation | Science Signaling

Frontiers | The Therapeutic Potential of Targeting NIK in B Cell Malignancies
Frontiers | The Therapeutic Potential of Targeting NIK in B Cell Malignancies

NIK SMI1 | NF-κB Inhibitor | MedChemExpress
NIK SMI1 | NF-κB Inhibitor | MedChemExpress

Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing)
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing)

NIK compounds* inhibit NFkB activation mediated by Smac-mimetic in MM... | Download Scientific Diagram
NIK compounds* inhibit NFkB activation mediated by Smac-mimetic in MM... | Download Scientific Diagram

Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A

IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML

NF-κB inducing kinase (NIK) inhibitors: Identification of new scaffolds using virtual screening - ScienceDirect
NF-κB inducing kinase (NIK) inhibitors: Identification of new scaffolds using virtual screening - ScienceDirect

NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways. - Abstract - Europe PMC
NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways. - Abstract - Europe PMC

SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation | Science Signaling
SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation | Science Signaling

IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML

NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways | Cell Death & Disease
NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways | Cell Death & Disease

NF-κB Signaling | NF-kappaB Pathway
NF-κB Signaling | NF-kappaB Pathway

Noncanonical NF-κB Signaling in Health and Disease: Trends in Molecular Medicine
Noncanonical NF-κB Signaling in Health and Disease: Trends in Molecular Medicine

IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML

Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets | HTML
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets | HTML

Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases | Translational Psychiatry
Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases | Translational Psychiatry

IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML

NF-kB pathway overview| Abcam
NF-kB pathway overview| Abcam

Role of NF-κB in the skeleton | Cell Research
Role of NF-κB in the skeleton | Cell Research

NF-κB-IN-1 | ≥99%(HPLC) | Selleck | NF-κB inhibitor
NF-κB-IN-1 | ≥99%(HPLC) | Selleck | NF-κB inhibitor